中文基本复合名词短语语义关系体系及知识库构建

名词短语一直是中外语言学领域的重要研究对象,近年来在自然语言处理领域也受到了研究者的持续关注。英文方面,已建立了一定规模的名词短语语义关系知识库。但迄今为止,尚未建立相应或更大规模的描述名词短语语义关系的中文资源。该文借鉴国内外诸多学者对名词短语语义分类的研究成果,对大规模真实语料中的基本复合名词短语实例进行试标注与分析,建立了中文基本复合名词短语语义关系体系及相应句法语义知识库,该库能够为中文基本复合名词短语句法语义的研究提供基础数据资源。目前该库共含有18 281条高频基本复合名词短语,每条短语均标注了语义关系、短语结构及是否指称实体等信息,每条短语包含的两个名词还分别标注了语义类信息。语义类信息基于北京大学《现代汉语语义词典》。基于该知识库,该文还做了基本复合名词短语句法语义的初步统计与分析。     

重庆市药物临床试验机构现状分析及地区性机构体系构建的思考

目的：重庆市具有丰富的医药产业底蕴和极佳的医疗资源，在我国药品注册审评制度改革紧密推进和重庆市大力发展生物医药产业的大背景下，本课题从对重庆市药物临床试验机构（以下简称机构）管理人员调研的角度入手，旨在明确重庆市机构建设现状与问题，探讨可行的创新发展对策。方法：本研究对我市20家有药物临床试验资质机构的54位管理人员问卷数据进行统计；并通过比对相应的公共数据，系统分析我市机构建设水平。结果：问卷分析显示，我市机构仍以传统GCP架构模式为主；以承担国内企业项目为主（90.00%），65.00%的机构近三年承接项目总数在40项以下；机构管理者多数从事机构相关工作的工作年限多在6年以内（79.59%），且仍有部分机构管理者未接受系统的培训；对公共数据调查分析显示，截至2019年5月底，我市机构总数目为22家，自2017年7月22日以来承接在Clinical Trails注册的在研项目数为81项，远低于机构工作开展较好的城市（北京：61家，433项；上海：53家，326项）。结论：重庆市机构建设水平亟待提高，应整合全市临床研究资源，构建区域化的药物临床试验机构体系，加速重庆市医药产业的创新发展。     

Knowledge-Based Virtual Modeling and Simulation of Manufacturing Processes for Industry 4.0

Abstract

Industry 4.0 aims at providing a digital representation of a production landscape, but the challenges in building, maintaining, optimizing, and evolving digital models in inter-organizational production chains have not been identified yet in a systematic manner. In this paper, various Industry 4.0 research and technical challenges are addressed, and their present scenario is discussed. Moreover, in this article, the novel concept of developing experience-based virtual models of engineering entities, process, and the factory is presented. These models of production units, processes, and procedures are accomplished by virtual engineering object (VEO), virtual engineering process (VEP), and virtual engineering factory (VEF), using the knowledge representation technique of Decisional DNA. This blend of the virtual and physical domains permits monitoring of systems and analysis of data to foresee problems before they occur, develop new opportunities, prevent downtime, and even plan for the future by using simulations. Furthermore, the proposed virtual model concept not only has the capability of Query Processing and Data Integration for Industrial Data but also real-time visualization of data stream processing.     

A knowledge construction methodology to automate case-based learning using clinical documents

The case-based learning (CBL) approach has gained attention in medical education as an alternative to traditional learning methodology. However, current CBL systems do not facilitate and provide computer-based domain knowledge to medical students for solving real-world clinical cases during CBL practice. To automate CBL, clinical documents are beneficial for constructing domain knowledge. In the literature, most systems and methodologies require a knowledge engineer to construct machine-readable knowledge. Keeping in view these facts, we present a knowledge construction methodology (KCM-CD) to construct domain knowledge ontology (i.e., structured declarative knowledge) from unstructured text in a systematic way using artificial intelligence techniques, with minimum intervention from a knowledge engineer. To utilize the strength of humans and computers, and to realize the KCM-CD methodology, an interactive case-based learning system(iCBLS) was developed. Finally, the developed ontological model was evaluated to evaluate the quality of domain knowledge in terms of coherence measure. The results showed that the overall domain model has positive coherence values, indicating that all words in each branch of the domain ontology are correlated with each other and the quality of the developed model is acceptable.     

一次性使用医用手套标准解读

一次性医用手套是能够防止人们交叉感染的常用防护用品。随着新冠肺炎疫情在全球范围的迅速蔓延,疫情防控一线以及广大普通民众对一次性医用手套的需求与日俱增,其标准也受到广泛关注。本文对中国国家标准涉及一次性使用医用手套的4项产品标准进行了解读,并分析它们与国外同种产品标准间的对应关系以及重点指标的差异。     

基于亲生物理论的医疗空间色彩设计研究

人类在漫长的进化过程中形成了对自然的本能需求,亲生物设计从生物进化的角度以更系统和更合理的方法将自然重新融入现代建筑环境,构建人与场所之间的积极交互。源于光、水、风、植物、动物等自然元素的亲生物色彩设计具有令人愉悦的艺术感染力,动态的视觉效果暗示着蓬勃的生命力,能够系统、清晰地传递复杂的环境信息,引发观者的情感共鸣和情感依恋。从环境疗愈的角度看,具有亲生物特征的色彩设计对改善患者在医疗空间中的体验,激发患者的自我康复能力具有重要意义。亲生物设计是可持续发展设计中不可或缺的一环,两者的结合有助于创造兼具低环境影响和高情感联系的设计,以实现真正和持久的可持续性发展。     

Negative statements considered useful

Knowledge bases (KBs) about notable entities and their properties are an important asset in applications such as search, question answering and dialog. All popular KBs capture virtually only positive statements, and abstain from taking any stance on statements not stored in the KB. This paper makes the case for explicitly stating salient statements that do not hold. Negative statements are useful to overcome limitations of question answering systems that are mainly geared for positive questions; they can also contribute to informative summaries of entities. Due to the abundance of such invalid statements, any effort to compile them needs to address ranking by saliency. We present a statistical inference method for compiling and ranking negative statements, based on expectations from positive statements of related entities in peer groups. Experimental results, with a variety of datasets, show that the method can effectively discover notable negative statements, and extrinsic studies underline their usefulness for entity summarization. Datasets and code are released as resources for further research.     

Visualization analysis of heart diseases using two‐dimensional electrocardiogram sequences

During the last years, there have been large advances in the understanding of cardiac mechanics, and in particular shape, motion and deformation. However, it is important to comprehend how these features interrelate and how they can be interpreted to refine the clinical diagnosis. The goal of our study is to illustrate the use of two‐dimensional ultrasound cardiac motion sequences on some typical cardiac pathologies. The method is applied to preprocessed data from two‐dimensional ultrasound sequences of four different subjects, namely, two healthy volunteers, one patient with left ventricular mechanical dyssynchrony from the left bundle branch block, and one patient with hypertrophic cardiomyopathy. The interpretation based on these features is corroborated with other analyzing techniques such as electrocardiogram and visual interpretation by experienced clinical observers. The proposed method realizes a computer program, which allows the user to easily obtain and visualize information about myocardial shape, motion (displacement and velocity), and deformation (strain) along the left ventricle myocardium wall during the cardiac cycle.